The objective of this work is to synthesize zinc oxide nanoparticles using chemical method and characterize zinc oxide nanoparticles using scanning electron microscope and xray diffractometer. Original article antibacterial activities of zinc oxide. Bovine mastitis causes severe economic loss to the dairy industry 1 and poses considerable risks to. Oct 15, 2011 the antibacterial activities of magnesium oxide nanoparticles mgo np alone or in combination with other antimicrobials nisin and zno np against escherichia coli o157. Pdf antibacterial activity of zno nanoparticle on gram. The antibacterial activity increased with increasing concentration of zinc oxide nanoparticles. Antibacterial activity of zinc oxide nanoparticles synthesized by solochemical process brailian journal of chemical ngineering, ol. Antibacterial surfaces with activity against antimicrobial. Here we get a new line of high purity zinc oxide nanoparticles primarily targeted for antimicrobial activity against bacillus subtilis and escherichia coli. Stock cultures were prepared by inoculating the strains in tryptone soya agar tsa himedia, india, followed by. We show that polyurethane containing crystal violet cv and 34 nm zinc oxide nanoparticles zno nps possesses excellent bactericidal activity against hospitalacquired pathogens including multidrug resistant.
In several studies the antimicrobial effect of zinc oxide coatings against different bacteri a can be already verified 2023. Antibacterial activity of zinc oxide and ag doped zinc. Acinetobacter baumannii is a multidrug resistant opportunistic pathogen, which causes respiratory and urinary tract infections. Determination of the antibacterial activity of metal oxide nanoparticles. Preprint title synthesis and characterization of zinc and copper oxide nanoparticles and their antibacterial activity authors richard b. Zno nanopowders are available as powders and dispersions.
Further its antimicrobial activity against bacillus subtilis and escherichia coli is studied. Pdf synthesis and characterization of zinc and copper oxide. Both nanozinc oxide and bulk zinc oxide are 4080fold less toxic than znso 4 against v. The oxidative stress damages lipids, carbohydrates, proteins. Original article antibacterial activities of zinc oxide nanoparticles against escherichia coli o157. Zno nanoparticle, antibacterial properties, ultrasonic method, antibiotic. Mydin1, srimala sreekantan2, khairul arifah saharudin2, khor yong ling2, norfatehah basiron2. It is demonstrated here that zinc oxide nanoparticles zno. Antibacterial activity of silver and zinc nanoparticles against vibrio cholerae and enterotoxic escherichia coli author links open overlay panel wesam salem a b deborah r. Jan 22, 2020 synthesis and characterization of zinc and copper oxide nanoparticles and their antibacterial activity preprint pdf available january 2020 with 85 reads how we measure reads. However, chemical methods are more suitable for industrial scale production 35 due to its low efficiency and.
Zinc oxide nanoparticles znonps were synthesized by the solgel method at various ph values. To identify the agents with potential antibacterial effects, six metal oxide nanoparticles mgo, tio 2, al 2 o 3, cuo, ceo 2 and zno were selected for our preliminary studies in liquid broth culture with aeration. Superior antibacterial activity of zinc oxidegraphene oxide. Zno nanoparticles can be obtained by physical and chemical routes. Zinc in nanoparticles form is more toxic to bacteria than their micron equivalents w. In the past two decades, zno nps have become one of the most popular metal oxide nanoparticles in biological applications due to their excellent biocompatibility, economic, and low toxicity. Influence of ph variations on zinc oxide nanoparticles and. Zinc oxide and titanium dioxide nanoparticles comprise wellknown inhibitory and bactericidal effects. Antibacterial zinc oxide nanoparticle coating of polyester. For the development of antibacterial textiles for applications on a large scale, e.
When the size is 12 nm, it inhibits the growth of s. Mar, 2014 formation of biofilms is the main contributing factor to antibiotic resistance. The antimicrobial activity of nanoparticles has been studied largely with human pathogenic bacteria, mainly li and s. Vibrio cholerae and enterotoxic escherichia coli etec remain two dominant bacterial causes of severe secretory diarrhea and still a significant cause of death, especially in developing countries. Zno nanoparticles against pathogenic bacteria and fungi. Nanoparticles the size of zno nanoparticles influences color, release of zn ions, and particle distribution as well as roughness of the coated surface. Particle size concentration of zinc oxide nanoparticles antibacterial activity by agar well diffusion method. The antibacterial effect of zinc oxide zno nanoparticles on campylobacter jejuni was investigated for inhibition and inactivation of cell growth. Sizedependent bacterial growth inhibition and mechanism.
Antimicrobial activity of zinc oxide nanoparticles it is universally known that zinc oxide nanoparticles are antibacterial and inhibit the growth of microorganisms by permeating into the cell membrane. Antibacterial activity of zinc oxide nanoparticles znonps has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. The results show that the zno nanoparticles have bacteriostatic activity against e. Antibacterial activities of zinc oxide nanoparticles. Zno nanoparticles have significantly higher antibacterial effect on s. This article provides further detail on the properties and applications of zinc oxide nanoparticles zno. To investigate antibacterial activities of zinc oxide nanoparticles zno np and their mode of action against an important foodborne pathogen, escherichia coli o157. Asamoah, abu yaya, bismark mensah, pascal nbelayim, vitus apalangya, yaw d. Xrd, ftir, fesem, uvvis and pl were accomplished to characterize the structural, functional groups, morphology, and optical properties of the samples. The fabricated nanocomposites were characterized by various techniques including x.
Zinc oxide nanoparticles zno nps are used in an increasing number of industrial products such as rubber, paint, coating, and cosmetics. Antibacterial activity and mechanism of action of zinc oxide nanoparticles against campylobacter jejuni yanping xie, 1yiping he, 2 peter l. This study was carried out to determine the antimicrobial activity of zinc oxide zno nanoparticle against isolated staphylococcus aureus. In vitro evaluation of antibacterial properties of zinc oxide. Feb 04, 2011 the antibacterial effect of zinc oxide zno nanoparticles on campylobacter jejuni was investigated for inhibition and inactivation of cell growth. The antibacterial activity of the zno nanoparticles was inversely proportional to the. The development of reliable processes for the synthesis of zinc oxide nanoparticles is an important aspect of nanotechnology today. Zinc oxide zno is a provocative material for applications in electronics, photonics, acoustics and sensing. Zingl a 1 gebhart schratter c ruth prassl c walter goessler d joachim reidl a stefan schild a. Antibacterial activity of zinc oxide nanoparticles on staphylococcus aureus article pdf available april 2016 with 2,274 reads how we measure reads. Enhanced antibacterial activity of capped zinc oxide. Zinc is a block d, period 4 element, while oxygen is a block p, period 2 element. Green synthesis and characterization of zinc oxide. Antibacterial activity of modified zinc oxide nanoparticles.
Zinc oxide zno nanoparticles have received a remarkable consideration due to their extra ordinary uv filtering properties, photochemical antifungal, high catalytic and antibacterial activities. In this study, the antimicrobial activity of titanium dioxide tio2, zinc oxide zno, and tio2zno nanoparticles supported into 4a zeolite 4a z was. Nov 25, 2019 in this study, the antimicrobial activity of titanium dioxide tio2, zinc oxide zno, and tio2zno nanoparticles supported into 4a zeolite 4a z was assessed. Znonps is a biosafe material, nontoxic to human cells sirelkhatim et al. They exhibit antibacterial, anticorrosive, antifungal and uv filtering properties. Zinc oxide nano particles are better antibacterial agent 2122. Zno is currently listed as a generally recognized as safe gras material by the food and drug administration and is used as food additive. Antibacterial activity of zno nanoparticle suspensions on. Nanoparticles zinc oxide antibacterial antifungal reactive oxygen species. These studies demonstrate that zno nanoparticles have a wide range of antibacterial activities toward various microorganisms that are commonly found in environmental settings. The results of the study confirmed that the zinc oxide nanoparticles may serve as promising antibacterial agents. Antimicrobial activity of titanium dioxide and zinc oxide. Antibacterial activity of zinc oxide nanoparticles against. The antibacterial effect of zinc oxide zno nanoparticles on campylobacter jejuni was.
The antibacterial activity of zno is dependent on the size and concentration of the particles. Pdf characterization and antibacterial activity of zno. Incorporated zinc oxide graphene oxide and its antibacterial. Rekha k, nirmala m, nair m g and anukaliani a 2010 structural, optical, photocatalytic and antibacterial activity of zinc oxide and manganese doped zinc oxide nanoparticles phys b condens matter. Synthesis, characterization, and antimicrobial activity of. Thus, zno in nanoscale has shown antimicrobial properties. In the present study the antibacterial activity of zinc oxide zno nanoparticles was investigated against gram negative escherichia. Antibacterial activity of zinc oxide nanoparticles against toxigenic bacillus cereus and staphylococcus aureus isolated from some egyptian food azza a. Green synthesis of zinc oxide nanoparticles znonps. Pdf antibacterial activity of zinc oxide nanoparticles znonps has received significant interest worldwide particularly by the implementation of. Synthesis and characterization of zinc and copper oxide nanoparticles and their antibacterial activity preprint pdf available january 2020 with 85 reads how we measure reads.
Antibacterial activity of dental composites containing. Antibacterial activity and mechanism of action of zinc oxide. Zno np with sizes of 70 nm and concentrations of 0, 3, 6 and 12 mmol l. The advent of nanotechnology has led the development of materials with new properties for use as antimicrobial agents. Therefore, we aimed in this study to test the antibacterial activity of zno nanoparticles on important and perilous bacteria such as. Therefore, zno nanoparticles which are differ in particle size should be used to achieve optimal properties of an antibacterial coating. Antimicrobial behavior of zinc oxide nanoparticles and. Pdf the aim of the present study is to determine the antimicrobial activity of zno nanoparticles against gramnegative and grampositive bacteria find. The fabrication, characterization, and antibacterial activity of novel nanocomposites based on graphene oxide go nanosheets decorated with silver, titanium dioxide nanoparticles, and zinc oxide nano. Antibacterial activity and mechanism of zno nanoparticles on. The antibacterial properties of zinc oxide nanoparticles were investigated using both grampositive and gramnegative microorganisms. All english, spanish, and portuguese articles related to the topic that were published.
Antimicrobial activity of zinc and titanium dioxide. Properties of zinc oxide nanoparticles and their activity. Methods to inhibit biofilm growth on dental composites have been sought for several decades. The investigation will compare their respective antibacteria activity against escherichia coli e. In the composites, zno nanoparticles nps, with a size of about 4. Growth kinetics and disk diffusion assay showed that znonp demonstrated good antibacterial activity against carbapenem resistant a. Mostafa department of biological and environmental science, faculty of home economics, al azhar univ. Synthesis and characterization of zinc and copper oxide. Recently, the green synthesis of zinc oxide nanoparticles have been a. Taking advantage of zinc oxide zno and graphene oxide go, the znogo composites were prepared by a facile onepot reaction to achieve superior antibacterial properties without damaging other species. Sizedependent bacterial growth inhibition and mechanism of.
Antimicrobial activity of zno nanoparticles against. Zinc oxide nanoparticles ailanthus altissima fruits antibacterial activity the green synthesis of nanoparticles using plants fruits aqueous extracts have been prepared for different applications. The antibacterial activity against li was investigated under photocatalytic light setup equipped with 250watts halogen lamp. The advancing of zinc oxide nanoparticles for biomedical. Carbapenems betalactam are most effective antibiotics till now against a. Zno nps have emerged a promising potential in biomedicine. The antibacterial activity of znonps was tested against grampositive bacteria, bacillus cereus atcc 11778 and staphylococcus aureus atcc 25923, and gramnegative bacteria, pseudomonas aeruginosa atcc 27853 and salmonella typhimurium atcc 1428. Pdf synthesis and characterization of zinc and copper. Shapedependent antibacterial activity against staphylococcus aureus of zinc oxide nanoparticles nor hazliana harun1, rabiatul basria s. Antibacterial activity of zno nanoparticle suspensions on a. Antimicrobial activity of cerium oxide nanoparticles on. Mydin1, srimala sreekantan2, khairul arifah saharudin2, khor yong ling2, norfatehah basiron2, fakhrul radhi4 and azman seeni1,3. Nps blended at 10% ww fraction into dental composites display antimicrobial activity and reduce growth of bacterial biofilms by roughly 80% for a single.
Damoah, benjamin agyeituffour, david dodooarhin and ebenezer annan publication date 22 jan 2020. Zinc oxide zno is an inorganic compound widely used in everyday applications. Biosynthesis, characterization, and antibacterial activity of zinc oxide nanoparticles derived from bauhinia tomentosa leaf extract g. Graphene oxide decorated with zinc oxide nanoflower. Shapedependent antibacterial activity against staphylococcus. In order to investigate new effective and inexpensive therapeutic approaches, we analyzed nanoparticles synthesized by a green approach using corresponding salt silver or zinc nitrate with aqueous. Zinc oxide nanoparticles prepared from the solution of zinc acetate, peg and ammonium carbonate. The zinc oxide zno nanoparticles were successfully synthesized by using aqueous extracts of aloe vera gelleaf and hibiscus sabdariffa leaf, and characterized by ft ir, uvvis, xrd, sem, and edx techniques. Zno exhibits significant antimicrobial activities when particle size is reduced to the nanometer range, then nanosized zno can interact with. Antibacterial activity of zno nanoparticle on grampositive and gramnegative bacteria article pdf available in african journal of microbiology research 518 june 2012 with 9,764 reads. Antibacterial activity of zinc oxide nanoparticles on staphylococcus aureus seyedeh atefe aleaghil 1,3, esmail fattahy 2, basireh baei 1,3, mansour saghali 3, hanieh bagheri 3, naeme javid 3.
Oct 17, 2012 the results showed that zinc oxide nanoparticles have strong antimicrobial activity against all tested pathogens. The compensation of using these metal oxides nanoparticles as antimicrobial agents is their better efficiency on resistant bacteria, less toxicity and heat resistance, and among metal oxide nanoparticles, zno nanoparticles have many significant features such as chemical and physical stability, high catalysis activity and effective. Antibacterial activity and mechanism of action of zinc. A vast number of published studies have used zinc oxide nanoparticles znonps as an antibacterial agent sirelkhatim et al.
Despite the significant antibacterial activity of zinc, one of the limiting factors in the use of zinc as nanoparticles is due to the different effective antibacterial concentration against s. Zinc oxide nanoparticles znonps are attractive as broadspectrum antibiotics, however, their further engineering as antimicrobial agents and clinical translation is impeded by controversial data about their mechanism of activity. It is commonly reported that znonps antimicrobial activity is associated w national nanotechnology day celebrating our 2018 prize and award winners. Mechanism of antibacterial activity of zinc oxide nanoparticle. Pdf antibacterial activity of zinc oxide nanoparticles. For the retrieval and selection of articles, the following keywords were used.
Antibacterial activity of zinc oxide and ag doped zinc oxide. However, chemical methods are more suitable for industrial scale. New materials with good antibacterial activity and less toxicity to other species attract numerous research interest. Green synthesized zinc oxide nanoparticles exhibit multifunctional behaviors and dynamic antibacterial activity 24. For comparison purposes, zno nanoparticles was also synthesized by chemical method. Pdf antibacterial activity of zinc oxide nanoparticles on. Superior antibacterial activity of zinc oxidegraphene. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. Pdf antibacterial activity of zno nanoparticle on grampositive.
Initial cell concentration was around 109 cfu ml1, and aqueous znonps suspensions ranged. Unexpected insights into antibacterial activity of zinc. But the ag doped zinc oxide nanoparticles showed better antibacterial activity than the zno nanoparticles. Apr 19, 2015 antibacterial activity of zinc oxide nanoparticles znonps has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. Zno np with sizes of 70 nm and concentrations of 0, 3, 6 and 12 mmol l1 and npfree solutions were used in antimicrobial tests against e. Antibacterial activity of silver and zinc nanoparticles. Biosynthesis, characterization, and antibacterial activity. The antibacterial activities of magnesium oxide nanoparticles mgo np alone or in combination with other antimicrobials nisin and zno np against escherichia coli o157. The results show that mgo np have strong bactericidal activity against the pathogens, achieving more than 7 log reductions in bacterial counts. Synthesis,characterization and antibacterial properties of zinc oxide nanoparticles 47 particle size, morphology and structure 3537. Its prevalence increases gradually in the clinical setup.
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